L-DEP-DB, Leishmania Differentially Expressed Protein DataBase, is a collection of inforamtion of proteins that are differntially expressed in proteomic study (invitro or invivo study) involving Leishmania parasite or Leishmanial infection. This database is a result of the systematic review. Articles published between 2000 and 2019 were considered for this study and for this review they were classified into five groups namely differential protein expression studies upon Leishmania infection, differential protein expression studies between different strains of Leishmania, differential protein expression studies on drug resistance towards Leishmaniasis, differential protein expression studies during stress on Leishmania, and differential protein expression studies on different life stages of Leishmania. A total of 2635 records are made available in the database and we believe it will help the research community in performing targeted proteomics study related to Leishmania.
No login or subscription is required for browsing/searching/ downloading data from the database.
The database interface is user-friendly and most of the features are self-descriptive, for any queries please contact saravanan.vij@icmr.gov.in
The database search settings allow one to search the database using different filters.
Description of each filter can be obtained by clicking "i" next to corresponding field in the "Query Filter" panel.
By default, when the "Search DB" page is browsed, the page loads all the records in the database and lists all 2,635 records.
Users can apply one or more filters, according to their need. The filter fields are dynamic and hence, the changes made to the filters will be reflected in the result table instantly.
Once a filter is applied, only the records satisfying the filter criteria will be loaded in the output table. The total number of records, after applying various filter, can be seen below the export option buttons.
Number of records to be displayed in the table at-a-time can be managed through "Show entries" box at the bottom of output table. The default display record is 5.
Each column can be sorted "ascending" or "descending" using the sort button available near the column header.
The output table page can be scrolled with the help of "Scroll page buttons" at the bottom of the output table.
The filter fields contain either a "Text box" or "Drop-down menu" or "Range box" for the user to provide filter input. Text can be enterd directly into the "Text box" as well as "Range box", but not into "Drop-down list". Also, the first box of the "Range box" is for entering minimum value and the second box for entering maximum value. Only one value can be selected from "Drop-down menu" at a time.
A click on any “PMID” or “Uniprot” will lead to specific article in pubmed database and protein details in Uniprot database, respectively.
Export and Download options are available on top of the result table.
The export options include exporting the filtered records to COPY as tab delimited text, to export as CSV, or to export as EXCEL file.
